Acetazolamide sodium

CAS No. 1424-27-7

Acetazolamide sodium( —— )

Catalog No. M35403 CAS No. 1424-27-7

Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and altitude sickness.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 36 Get Quote
1G 45 Get Quote

Biological Information

  • Product Name
    Acetazolamide sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and altitude sickness.
  • Description
    Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Carbonic Anhydrase
  • Recptor
    Carbonic Anhydrase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1424-27-7
  • Formula Weight
    244.23
  • Molecular Formula
    C4H5N4NaO3S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : ≥ 100 mg/mL (407.76 mM)DMSO : 100 mg/mL (407.76 mM; Ultrasonic )
  • SMILES
    O=C(C)NC1=NN=C(S(=O)([NH-])=O)S1.[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bayat Mokhtari R, et al.Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 2017 Feb 24;17(1):156.?
molnova catalog
related products
  • hCAI/II/IV-IN-28

    hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.

  • CAIX Inhibitor S4

    CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM.

  • Enpp/Carbonic?anhydr...

    Enpp/Carbonic?anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.